This volume describes a range of standard and novel methodological approaches used to probe ion channel function across different modalities. Chapters guide readers through methods and protocols from an introduction to the decades old patch clamp method for the ion channel neophyte to more complex, recent protocol advances, such as optogenetics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Patch Clamp Electrophysiology: Methods and Protocols aims to be a reference guide for current and future ion channel physiologists.

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Many Pizza Recipes to choose from. Find Pizza dough recipes and pizza sauce recipes, as well as pizza for everyone’s taste. There is Vegetarian Pizza recipes, Mexican Pizza, California Pizza, Cheese Pizza, Mushroom Pizza, Ham and Pineapple Pizza, and Dessert Pizza, too. There is even a special Diabetic recipe for Pizza. There is Hot Pizza’s and Cold Pizza’s, lots of Pizza’s!! There are a few “secrets of the trade” in making your own pizza; once you know them, it is not hard to make your own and it takes very little time. In fact, after you make it a few times you’ll wonder why I made such a big deal out of it. Inside you will find Hot and Delicious Pizza Recipes.

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This book opens with a brief introduction to renewable energy and the advantages of solar energy systems, an overview of concentrated solar power (CSP) system technologies and modeling, and the application of artificial neural network (ANN) technologies in various solar field systems. Later chapters cover data and operation methods of central tower receiver power plants (CTRPP), important models of ANN techniques used in solar energy fields, accurate methods for modeling CTRPP, the economics of solar energy systems, the CSP impacts on the penetration level of photovoltaic (PV) systems, and a look at the reliability of systems using case studies on PV systems and hybrid PV and CSP systems.

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The twentieth century witnessed the birth of revolutionary ideas in the phys­ ical sciences. These ideas began to shake the traditional view of the universe dating back to the days of Newton, even to the days of Galileo. Albert Ein­ stein is usually identified as the creator of the relativity theory, a theory that is used to model the behavior of the huge macrosystems of astronomy.

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From the authors of Pinch of Nom, the fastest selling non-fiction book in the UK. Losing weight has never been easier with the cookbook that does the maths for you, from the no.1 bestselling authors of Pinch of Nom.

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Worried about potty training? Let Jamie Glowacki, potty-training expert at OhCrapPottyTraining.com, show you how it’s done. Jamie Glowacki—potty-training expert, Pied Piper of Poop, and author of the popular guide, Oh Crap! Potty Training—shares her proven 6-step plan to help you toilet train your preschooler quickly and successfully.

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Nothing defines a person like their hairstyle – and what a century it has been for hair! Bangs, bobs, buns, beehives and bouffants have vied with pixie cuts, pin curls, perms and pageboys for ascendancy in an ever-changing parade of ladies’ looks and trends, and among the men we’ve seen Caesers, comb overs, ducktails, faux hawks, flattops, quiffs and slick backs. From the Edwardian era through the seismic changes of the ’20s and ’60s, and including every quirky twist hair history took on its way to the turn of the millennium, this book is a lush visual survey of a hundred years of hair styles and the great stylists of the century including Jackie Kennedy’s stylist Mr. Kenneth and innovators like Vidal Sassoon.

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Greetings often provide designers with the chance to truly stretch their creative wings through personal expression. The follow-up to 1,000 Greetings, 1,000 More Greetings highlights a diverse cross section of current trends in graphic design. Corporate cutbacks and increased electronic connectivity are each variables that have contributed to the democratization of design in recent times, and the collection in this book reflects that. Everything from mass-produced to limited-edition pieces, from hand-drawn to computer-generated art, from conventional to renegade printing methods are all represented side-by-side in this compilation.

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Decades of research have demonstrated that normal aging is accompanied by cognitive change. Much of this change has been conceptualized as a decline in function. However, age-related changes are not universal, and decrements in older adult performance may be moderated by experience, genetics, and environmental factors. Cognitive aging research to date has also largely emphasized biological changes in the brain, with less evaluation of the range of external contributors to behavioral manifestations of age-related decrements in performance. This handbook provides a comprehensive overview of cutting-edge cognitive aging research through the lens of a life course perspective that takes into account both behavioral and neural changes. Focusing on the fundamental principles that characterize a life course approach – genetics, early life experiences, motivation, emotion, social contexts, and lifestyle interventions – this handbook is an essential resource for researchers in cognition, aging, and gerontology.

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It’s Monday morning and George walks out the front door to his car and a flat tire. But this is the least of his problems. His home life is in shambles and his team at work is in disarray. With a big new product launch coming up in 2 weeks for the NRG-2000 he has to find a way to get it together or risk losing his marriage and job. Forced to take the bus to work, George meets a unique kind of bus driver and an interesting set of characters (passengers) that over the course of 2 weeks share the 10 rules for the ride of his life… and attempt to help him turn around his work and team and save his job and marriage from an almost inevitable destruction.

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Get ready for adorably decorated and deliciously flavored cupcakes made easy! Betty Crocker The Big Book of Cupcakes features 175 delightful cupcakes, all using new and fun decorating ideas anyone can master and simple ingredients available anywhere. And as a unique feature, almost every cupcake can be made from scratch or with a mix: You decide which method to follow.

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Reflecting training and experience in both Eastern and Western medicine, this reference uses a scientific perspective to shed light on the teaching and practices of traditional Chinese medicine (TCM). In addition to examining the TCM approach to wellness and disease, the resource compares TCM to conventional Western approaches and shows the optimal way to integrate the two disciplines.

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